Consuelo Gajate Selected Research

Verapamil (Calan)

10/2018

Substitution at the indole 3 position yields highly potent indolecombretastatins against human tumor cells.

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Consuelo Gajate Research Topics

Disease

41	Neoplasms (Cancer) 01/2024 - 10/2002
4	Pancreatic Neoplasms (Pancreatic Cancer) 12/2021 - 04/2018
3	Multiple Myeloma 01/2020 - 01/2007
3	Mantle-Cell Lymphoma (Lymphoma, Mantle Cell) 01/2015 - 02/2009
2	Breast Neoplasms (Breast Cancer) 01/2024 - 04/2003
2	Adenocarcinoma 09/2022 - 04/2018
2	Neoplasm Metastasis (Metastasis) 01/2020 - 01/2016
2	Autoimmune Diseases (Autoimmune Disease) 11/2015 - 10/2002
2	Melanoma (Melanoma, Malignant) 04/2013 - 07/2011
2	Carcinoma (Carcinomatosis) 05/2006 - 02/2004
1	Prostatic Neoplasms (Prostate Cancer) 11/2023
1	Hypoxia (Hypoxemia) 08/2021
1	Acute Myeloid Leukemia (Acute Myelogenous Leukemia) 11/2019
1	Non-Small-Cell Lung Carcinoma (Carcinoma, Non-Small Cell Lung) 10/2018
1	Leishmaniasis 08/2017
1	Strongyloidiasis 10/2016
1	Infections 10/2016
1	Ewing Sarcoma (Sarcoma, Ewing) 06/2015
1	B-Cell Chronic Lymphocytic Leukemia (Chronic Lymphocytic Leukemia) 04/2010
1	Ulcer 05/2009
1	Edema (Dropsy) 05/2009
1	Cardiotoxicity 05/2009
1	Inflammation (Inflammations) 05/2009
1	Colitis 05/2009
1	Inflammatory Bowel Diseases (Inflammatory Bowel Disease) 05/2009
1	Hematologic Neoplasms (Hematological Malignancy) 03/2009
1	Severe Combined Immunodeficiency (Bare Lymphocyte Syndrome) 02/2009
1	Leukemia 01/2009
1	T-Cell Leukemia (Leukemia, T Cell) 01/2009

Drug/Important Bio-Agent (IBA)

29	edelfosineIBA 01/2024 - 10/2002
26	LipidsIBA 08/2021 - 10/2002
13	Death Domain ReceptorsIBA 05/2021 - 08/2004
9	Ether (Diethyl Ether)IBA 08/2021 - 10/2002
8	Antineoplastic Agents (Antineoplastics)IBA 08/2021 - 10/2002
6	Proteins (Proteins, Gene)FDA Link 01/2022 - 11/2005
5	LysophospholipidsIBA 09/2011 - 11/2005
4	TubulinIBA 01/2021 - 01/2005
4	Phospholipids (Phosphatides)FDA LinkGeneric 05/2014 - 10/2002
3	DNA (Deoxyribonucleic Acid)IBA 12/2021 - 10/2002
3	CaspasesIBA 04/2018 - 07/2011
2	CholesterolIBA 05/2021 - 01/2020
2	Bortezomib (Velcade)FDA Link 01/2020 - 07/2008
2	fosbretabulin (combretastatin A4)IBA 01/2020 - 10/2018
2	Caspase 3 (Caspase-3)IBA 10/2018 - 04/2003
2	perifosineIBA 08/2017 - 01/2007
2	plitidepsin (aplidine)IBA 07/2008 - 04/2003
1	CollagenIBA 01/2024
1	Laminin (Merosin)IBA 01/2024
1	Phosphoric Monoester Hydrolases (Phosphatases)IBA 11/2023
1	Phosphotransferases (Kinase)IBA 11/2023
1	AndrogensIBA 11/2023
1	TensinsIBA 11/2023
1	Nicotinamide PhosphoribosyltransferaseIBA 09/2022
1	Epithelial Cell Adhesion MoleculeIBA 12/2021
1	Mitochondrial Proteins (Mitochondrial Protein)IBA 05/2021
1	Arginine (L-Arginine)FDA Link 01/2021
1	Phosphatidylinositol 3-Kinase (1 Phosphatidylinositol 3 Kinase)IBA 01/2020
1	Proteasome InhibitorsIBA 01/2020
1	Insulin-Like PeptidesIBA 01/2020
1	Mucin-1 (CA 15-3 Antigen)IBA 01/2020
1	Glycoproteins (Glycoprotein)IBA 01/2020
1	pyridineIBA 01/2020
1	IntegrinsIBA 01/2020
1	protein-S-isoprenylcysteine O-methyltransferaseIBA 11/2019
1	Verapamil (Calan)FDA LinkGeneric 10/2018
1	Member 1 Subfamily B ATP Binding Cassette TransporterIBA 10/2018
1	indoleIBA 10/2018
1	pyrrolidineIBA 04/2018
1	Hydroxyl RadicalIBA 04/2018
1	1-cyano-2,3-epithiopropaneIBA 01/2018
1	erucylphosphocholineIBA 08/2017
1	miltefosine (Impavido)IBA 08/2017
1	1- O- hexadecyl- 2- O- methylglycero- 3- lactoseIBA 01/2016
1	Ion Channels (Ion Channel)IBA 01/2016
1	Therapeutic UsesIBA 01/2016
1	Dantrolene (Dantrium)FDA LinkGeneric 04/2013
1	sanguinarineIBA 04/2013
1	CalciumIBA 04/2013
1	Glutathione (Reduced Glutathione)IBA 04/2013
1	BerberineIBA 07/2011
1	Reactive Oxygen Species (Oxygen Radicals)IBA 07/2011
1	Apoptosis Inducing FactorIBA 07/2011
1	Adenosine Triphosphate (ATP)IBA 07/2011
1	Adenosine Diphosphate (ADP)IBA 07/2011
1	Cytochromes c (Cytochrome c)IBA 07/2011
1	Indomethacin (Indometacin)FDA LinkGeneric 05/2009
1	Bentonite (Montmorillonite)IBA 05/2009
1	Non-Steroidal Anti-Inflammatory Agents (NSAIDs)IBA 05/2009
1	L-SelectinIBA 05/2009
1	Apoptosomes (Apoptosome)IBA 03/2009
1	Caspase 8 (Caspase-8)IBA 01/2009
1	DepsipeptidesIBA 07/2008
1	Dexamethasone (Maxidex)FDA LinkGeneric 07/2008
1	Thalidomide (Thalomid)FDA Link 07/2008
1	AnthracyclinesIBA 07/2008
1	Alkylating AgentsIBA 07/2008

Therapy/Procedure

16	Therapeutics 01/2024 - 10/2002
7	Drug Therapy (Chemotherapy) 09/2022 - 10/2002
4	Oral Administration 11/2023 - 02/2009
1	Subcutaneous Injections 12/2021